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Heparan sulfate proteoglycan induces the production of NO and TNF-α by murine microglia
BACKGROUND: A common feature of Alzheimer's disease (AD) pathology is the abundance of activated microglia in neuritic plaques containing amyloid-beta protein (Aβ) and associated molecules including heparan sulfate proteoglycan (HSPG). Besides the role as pathological chaperone favouring amyloi...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208935/ https://www.ncbi.nlm.nih.gov/pubmed/16022734 http://dx.doi.org/10.1186/1742-4933-2-11 |