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Variation in structural location and amino acid conservation of functional sites in protein domain families

BACKGROUND: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods for the prediction of functional sites are of immense value. Most available methods are based on a set of homologous seq...

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Detalles Bibliográficos
Autores principales: Pils, Birgit, Copley, Richard R, Schultz, Jörg
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1215474/
https://www.ncbi.nlm.nih.gov/pubmed/16122386
http://dx.doi.org/10.1186/1471-2105-6-210