Production and characterization of amplified tumor-derived cRNA libraries to be used as vaccines against metastatic melanomas

BACKGROUND: Anti-tumor vaccines targeting the entire tumor antigen repertoire represent an attractive immunotherapeutic approach. In the context of a phase I/II clinical trial, we vaccinated metastatic melanoma patients with autologous amplified tumor mRNA. In order to provide the large quantities o...

Descripción completa

Detalles Bibliográficos
Autores principales: Carralot, Jean-Philippe, Weide, Benjamin, Schoor, Oliver, Probst, Jochen, Scheel, Birgit, Teufel, Regina, Hoerr, Ingmar, Garbe, Claus, Rammensee, Hans-Georg, Pascolo, Steve
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1215502/
https://www.ncbi.nlm.nih.gov/pubmed/16115316
http://dx.doi.org/10.1186/1479-0556-3-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1215502/
https://www.ncbi.nlm.nih.gov/pubmed/16115316
http://dx.doi.org/10.1186/1479-0556-3-6

Ejemplares similares