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Production and characterization of amplified tumor-derived cRNA libraries to be used as vaccines against metastatic melanomas

BACKGROUND: Anti-tumor vaccines targeting the entire tumor antigen repertoire represent an attractive immunotherapeutic approach. In the context of a phase I/II clinical trial, we vaccinated metastatic melanoma patients with autologous amplified tumor mRNA. In order to provide the large quantities o...

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Detalles Bibliográficos
Autores principales:	Carralot, Jean-Philippe, Weide, Benjamin, Schoor, Oliver, Probst, Jochen, Scheel, Birgit, Teufel, Regina, Hoerr, Ingmar, Garbe, Claus, Rammensee, Hans-Georg, Pascolo, Steve
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1215502/ https://www.ncbi.nlm.nih.gov/pubmed/16115316 http://dx.doi.org/10.1186/1479-0556-3-6

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