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PKQuest: volatile solutes – application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics
BACKGROUND: The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for this analysis. PKQuest is a new generic PBPK that is designed to avoid this problem by using a set of "standard...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC122062/ https://www.ncbi.nlm.nih.gov/pubmed/12182764 http://dx.doi.org/10.1186/1471-2253-2-5 |