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Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth

BACKGROUND: The outgrowth of new vessels – angiogenesis – in the tumour mass is considered to be a limiting factor of tumour growth. To inhibit the matrix lysis that is part of the tumour angiogenesis, we employed the chimeric protein mhATF-BPTI, composed of the receptor binding part of the urokinas...

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Detalles Bibliográficos
Autores principales: Lefesvre, Pierre, Attema, Joline, van Bekkum, Dirk
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC122087/
https://www.ncbi.nlm.nih.gov/pubmed/12147175
http://dx.doi.org/10.1186/1471-2407-2-17