Establishment of a doxycycline-regulated cell line with inducible, doubly-stable expression of the wild-type p53 gene from p53-deleted hepatocellular carcinoma cells

p53 is important in the development of hepatocellular carcinoma (HCC) and in therapeutic approaches, but the mechanism whereby it inhibits HCC growth is still unclear. The aim of the present study was to establish a HCC cell system in which p53 levels can be regulated. Full-length wild-type p53 cDNA...

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Detalles Bibliográficos
Autores principales: Chi, Tian-Yi, Chen, George G, Ho, Lok-Kee, Lai, Paul BS
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224858/
https://www.ncbi.nlm.nih.gov/pubmed/16117829
http://dx.doi.org/10.1186/1475-2867-5-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224858/
https://www.ncbi.nlm.nih.gov/pubmed/16117829
http://dx.doi.org/10.1186/1475-2867-5-27

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