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Tissue transglutaminase-induced alterations in extracellular matrix inhibit tumor invasion
BACKGROUND: Alterations in the extracellular matrix (ECM) can affect host-tumor interactions and tumor growth and metastasis. Tissue transglutaminase (TG2, EC 2.3.2.13), a calcium-dependent enzyme that catalyzes covalent cross-linking of proteins, can render the ECM highly stable and resistant to pr...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224867/ https://www.ncbi.nlm.nih.gov/pubmed/16153302 http://dx.doi.org/10.1186/1476-4598-4-33 |