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Tissue transglutaminase-induced alterations in extracellular matrix inhibit tumor invasion

BACKGROUND: Alterations in the extracellular matrix (ECM) can affect host-tumor interactions and tumor growth and metastasis. Tissue transglutaminase (TG2, EC 2.3.2.13), a calcium-dependent enzyme that catalyzes covalent cross-linking of proteins, can render the ECM highly stable and resistant to pr...

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Detalles Bibliográficos
Autores principales:	Mangala, Lingegowda S, Arun, Banu, Sahin, Aysegul A, Mehta, Kapil
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224867/ https://www.ncbi.nlm.nih.gov/pubmed/16153302 http://dx.doi.org/10.1186/1476-4598-4-33

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