Guanine and 7,8-dihydro-8-oxo-guanine-specific oxidation in DNA by chromium(V).

The hexavalent oxidation state of chromium [Cr(VI)] is a well-established human carcinogen, although the mechanism of cancer induction is currently unknown. Intracellular reduction of Cr(VI) forms Cr(V), which is thought to play a fundamental role in the mechanism of DNA damage by this carcinogen. T...

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Detalles Bibliográficos
Autores principales: Sugden, Kent D, Martin, Brooke D
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226306/
https://www.ncbi.nlm.nih.gov/pubmed/12426120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226306/
https://www.ncbi.nlm.nih.gov/pubmed/12426120

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