Possibility of selection against mtDNA mutations in tumors

Several studies of tumors have revealed substantial numbers of clonally expanded somatic mutations in mitochondrial DNA (mtDNA), not observed in adjacent intact tissues. These findings were interpreted as indicating the involvement of mtDNA mutations in tumorigenesis. Such comparisons, however, igno...

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Detalles Bibliográficos
Autores principales: Khaidakov, M, Reis, RJ Shmookler
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232865/
https://www.ncbi.nlm.nih.gov/pubmed/16159390
http://dx.doi.org/10.1186/1476-4598-4-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232865/
https://www.ncbi.nlm.nih.gov/pubmed/16159390
http://dx.doi.org/10.1186/1476-4598-4-36

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