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Nucleic acid chaperons: a theory of an RNA-assisted protein folding

BACKGROUND: Proteins are assumed to contain all the information necessary for unambiguous folding (Anfinsen's principle). However, ab initio structure prediction is often not successful because the amino acid sequence itself is not sufficient to guide between endless folding possibilities. It s...

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Detalles Bibliográficos
Autor principal: Biro, Jan C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232867/
https://www.ncbi.nlm.nih.gov/pubmed/16137324
http://dx.doi.org/10.1186/1742-4682-2-35