Cargando…

Mechanistic studies on DNA damage by minor groove binding copper–phenanthroline conjugates

Copper–phenanthroline complexes oxidatively damage and cleave nucleic acids. Copper bis-phenanthroline and copper complexes of mono- and bis-phenanthroline conjugates are used as research tools for studying nucleic acid structure and binding interactions. The mechanism of DNA oxidation and cleavage...

Descripción completa

Detalles Bibliográficos
Autores principales: Bales, Brian C., Kodama, Tetsuya, Weledji, Yvonne N., Pitié, Marguerite, Meunier, Bernard, Greenberg, Marc M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1235636/
https://www.ncbi.nlm.nih.gov/pubmed/16186134
http://dx.doi.org/10.1093/nar/gki856