Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways

We have synthesized triple helix forming oligonucleotides (TFOs) that target a psoralen (pso) interstrand crosslink to a specific chromosomal site in mammalian cells. Mutagenesis of the targeted crosslinks results in base substitutions and deletions. Identification of the gene products involved in m...

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Detalles Bibliográficos
Autores principales: Richards, Sally, Liu, Su-Ting, Majumdar, Alokes, Liu, Ji-Lan, Nairn, Rodney S., Bernier, Michel, Maher, Veronica, Seidman, Michael M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236719/
https://www.ncbi.nlm.nih.gov/pubmed/16186129
http://dx.doi.org/10.1093/nar/gki851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236719/
https://www.ncbi.nlm.nih.gov/pubmed/16186129
http://dx.doi.org/10.1093/nar/gki851

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