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Human-zebrafish non-coding conserved elements act in vivo to regulate transcription

Whole genome comparisons of distantly related species effectively predict biologically important sequences—core genes and cis-acting regulatory elements (REs)—but require experimentation to verify biological activity. To examine the efficacy of comparative genomics in identification of active REs fr...

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Detalles Bibliográficos
Autores principales: Shin, Jordan T., Priest, James R., Ovcharenko, Ivan, Ronco, Amy, Moore, Rachel K., Burns, C. Geoffrey, MacRae, Calum A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236720/
https://www.ncbi.nlm.nih.gov/pubmed/16179648
http://dx.doi.org/10.1093/nar/gki853