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Generalizations of Markov model to characterize biological sequences

BACKGROUND: The currently used k(th )order Markov models estimate the probability of generating a single nucleotide conditional upon the immediately preceding (gap = 0) k units. However, this neither takes into account the joint dependency of multiple neighboring nucleotides, nor does it consider th...

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Detalles Bibliográficos
Autores principales: Wang, Junwen, Hannenhalli, Sridhar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236913/
https://www.ncbi.nlm.nih.gov/pubmed/16144548
http://dx.doi.org/10.1186/1471-2105-6-219