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Euploidy in somatic cells from R6/2 transgenic Huntington's disease mice

BACKGROUND: Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a CAG repeat expansion in the HD gene. The huntingtin protein expressed from HD has an unknown function but is suggested to interact with proteins involved in the cell division machinery. The R6/2 transge...

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Detalles Bibliográficos
Autores principales: Petersén, Åsa, Stewénius, Ylva, Björkqvist, Maria, Gisselsson, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236918/
https://www.ncbi.nlm.nih.gov/pubmed/16159402
http://dx.doi.org/10.1186/1471-2121-6-34