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Evolutionary conservation suggests a regulatory function of AUG triplets in 5′-UTRs of eukaryotic genes
By comparing sequences of human, mouse and rat orthologous genes, we show that in 5′-untranslated regions (5′-UTRs) of mammalian cDNAs but not in 3′-UTRs or coding sequences, AUG is conserved to a significantly greater extent than any of the other 63 nt triplets. This effect is likely to reflect, pr...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236974/ https://www.ncbi.nlm.nih.gov/pubmed/16186132 http://dx.doi.org/10.1093/nar/gki847 |