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Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia

Extracellular adenosine has been widely implicated in adaptive responses to hypoxia. The generation of extracellular adenosine involves phosphohydrolysis of adenine nucleotide intermediates, and is regulated by the terminal enzymatic step catalyzed by ecto-5′-nucleotidase (CD73). Guided by previous...

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Detalles Bibliográficos
Autores principales: Thompson, Linda F., Eltzschig, Holger K., Ibla, Juan C., Van De Wiele, C. Justin, Resta, Regina, Morote-Garcia, Julio C., Colgan, Sean P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1237012/
https://www.ncbi.nlm.nih.gov/pubmed/15583013
http://dx.doi.org/10.1084/jem.20040915