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Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia
Extracellular adenosine has been widely implicated in adaptive responses to hypoxia. The generation of extracellular adenosine involves phosphohydrolysis of adenine nucleotide intermediates, and is regulated by the terminal enzymatic step catalyzed by ecto-5′-nucleotidase (CD73). Guided by previous...
Autores principales: | Thompson, Linda F., Eltzschig, Holger K., Ibla, Juan C., Van De Wiele, C. Justin, Resta, Regina, Morote-Garcia, Julio C., Colgan, Sean P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1237012/ https://www.ncbi.nlm.nih.gov/pubmed/15583013 http://dx.doi.org/10.1084/jem.20040915 |
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