Direct in vivo V(H) to J(H) rearrangement violating the 12/23 rule

V(D)J recombination at the immunoglobulin heavy chain (IgH) locus follows the 12/23 rule to ensure the correct assembly of the variable region gene segments. Here, we report characterization of an in vivo model that allowed us to study recombination violating the 12/23 rule, namely a mouse strain la...

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Detalles Bibliográficos
Autores principales: Koralov, Sergei B., Novobrantseva, Tatiana I., Hochedlinger, Konrad, Jaenisch, Rudolf, Rajewsky, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1237122/
https://www.ncbi.nlm.nih.gov/pubmed/15699070
http://dx.doi.org/10.1084/jem.20041577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1237122/
https://www.ncbi.nlm.nih.gov/pubmed/15699070
http://dx.doi.org/10.1084/jem.20041577

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