Interaction between Polyketide Synthase and Transporter Suggests Coupled Synthesis and Export of Virulence Lipid in M. tuberculosis

Virulent mycobacteria utilize surface-exposed polyketides to interact with host cells, but the mechanism by which these hydrophobic molecules are transported across the cell envelope to the surface of the bacteria is poorly understood. Phthiocerol dimycocerosate (PDIM), a surface-exposed polyketide...

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Detalles Bibliográficos
Autores principales: Jain, Madhulika, Cox, Jeffery S
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238737/
https://www.ncbi.nlm.nih.gov/pubmed/16201014
http://dx.doi.org/10.1371/journal.ppat.0010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238737/
https://www.ncbi.nlm.nih.gov/pubmed/16201014
http://dx.doi.org/10.1371/journal.ppat.0010002

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