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Inhibition of MHC Class I Is a Virulence Factor in Herpes Simplex Virus Infection of Mice
Herpes simplex virus (HSV) has a number of genes devoted to immune evasion. One such gene, ICP47, binds to the transporter associated with antigen presentation (TAP) 1/2 thereby preventing transport of viral peptides into the endoplasmic reticulum, loading of peptides onto nascent major histocompati...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238742/ https://www.ncbi.nlm.nih.gov/pubmed/16201019 http://dx.doi.org/10.1371/journal.ppat.0010007 |