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Inhibition of MHC Class I Is a Virulence Factor in Herpes Simplex Virus Infection of Mice

Herpes simplex virus (HSV) has a number of genes devoted to immune evasion. One such gene, ICP47, binds to the transporter associated with antigen presentation (TAP) 1/2 thereby preventing transport of viral peptides into the endoplasmic reticulum, loading of peptides onto nascent major histocompati...

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Detalles Bibliográficos
Autores principales:	Orr, Mark T, Edelmann, Kurt H, Vieira, Jeffrey, Corey, Lawrence, Raulet, David H, Wilson, Christopher B
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238742/ https://www.ncbi.nlm.nih.gov/pubmed/16201019 http://dx.doi.org/10.1371/journal.ppat.0010007

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