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Epigenetic inactivation and aberrant transcription of CSMD1 in squamous cell carcinoma cell lines

BACKGROUND: The p23.2 region of human chromosome 8 is frequently deleted in several types of epithelial cancer and those deletions appear to be associated with poor prognosis. Cub and Sushi Multiple Domains 1 (CSMD1) was positionally cloned as a candidate for the 8p23 suppressor but point mutations...

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Detalles Bibliográficos
Autores principales: Richter, Toni M, Tong, Benton D, Scholnick, Steven B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1239921/
https://www.ncbi.nlm.nih.gov/pubmed/16153303
http://dx.doi.org/10.1186/1475-2867-5-29