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Effects of ADMA upon Gene Expression: An Insight into the Pathophysiological Significance of Raised Plasma ADMA

BACKGROUND: Asymmetric dimethylarginine (ADMA) is a naturally occurring inhibitor of nitric oxide synthesis that accumulates in a wide range of diseases associated with endothelial dysfunction and enhanced atherosclerosis. Clinical studies implicate plasma ADMA as a major novel cardiovascular risk f...

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Detalles Bibliográficos
Autores principales: Smith, Caroline L, Anthony, Shelagh, Hubank, Mike, Leiper, James M, Vallance, Patrick
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240048/
https://www.ncbi.nlm.nih.gov/pubmed/16190779
http://dx.doi.org/10.1371/journal.pmed.0020264