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Effects of ADMA upon Gene Expression: An Insight into the Pathophysiological Significance of Raised Plasma ADMA
BACKGROUND: Asymmetric dimethylarginine (ADMA) is a naturally occurring inhibitor of nitric oxide synthesis that accumulates in a wide range of diseases associated with endothelial dysfunction and enhanced atherosclerosis. Clinical studies implicate plasma ADMA as a major novel cardiovascular risk f...
Autores principales: | Smith, Caroline L, Anthony, Shelagh, Hubank, Mike, Leiper, James M, Vallance, Patrick |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240048/ https://www.ncbi.nlm.nih.gov/pubmed/16190779 http://dx.doi.org/10.1371/journal.pmed.0020264 |
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