Formamidopyrimidine-DNA glycosylase enhances arsenic-induced DNA strand breaks in PHA-stimulated and unstimulated human lymphocytes.

To confirm that arsenic (As) induces oxidative DNA damage in phytohemagglutinin (PHA)-stimulated and unstimulated human lymphocytes, we used the alkaline comet assay combined with specific enzyme [formamidopyrimidine-DNA glycosylase (FPG)] digestion to measure As-induced base damage. The results sho...

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Detalles Bibliográficos
Autores principales: Li, D, Morimoto, K, Takeshita, T, Lu, Y
Formato: Texto
Lenguaje:English
Publicado: 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240313/
https://www.ncbi.nlm.nih.gov/pubmed/11401765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240313/
https://www.ncbi.nlm.nih.gov/pubmed/11401765

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