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Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.

We studied nine presumed nongenotoxic rodent carcinogens, as defined by the U.S. National Toxicology Program (NTP), to determine their ability to induce acute or subacute biochemical and tissue changes that may act as useful predictors of nongenotoxic rodent carcinogenesis. The chemicals selected in...

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Detalles Bibliográficos
Autores principales: Elcombe, Clifford R, Odum, Jenny, Foster, John R, Stone, Susan, Hasmall, Susan, Soames, Anthony R, Kimber, Ian, Ashby, John
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240799/
https://www.ncbi.nlm.nih.gov/pubmed/11940454