AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model.

The promotion-sensitive mouse epidermal JB6 cells (clone 41) have been used to identify the tumor-promoting activity of various compounds. Because treatment by tumor promoters [12-O-tetradecanoylphorbol-13-acetate (TPA), epidermal growth factor (EGF), or tumor necrosis factor alpha (TNF-alpha)] tran...

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Detalles Bibliográficos
Autores principales: Suzukawa, Kazumi, Weber, Thomas J, Colburn, Nancy H
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240984/
https://www.ncbi.nlm.nih.gov/pubmed/12204819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240984/
https://www.ncbi.nlm.nih.gov/pubmed/12204819

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