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Formation of reactive nitrogen species at biologic heme centers: a potential mechanism of nitric oxide-dependent toxicity.

The peroxidase-catalyzed nitration of tyrosine derivatives by nitrite and hydrogen peroxide has been studied in detail using the enzymes lactoperoxidase (LPO) from bovine milk and horseradish peroxidase (HRP). The results indicate the existence of two competing pathways, in which the nitrating speci...

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Detalles Bibliográficos
Autores principales: Casella, Luigi, Monzani, Enrico, Roncone, Raffaella, Nicolis, Stefania, Sala, Alberto, De Riso, Antonio
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241230/
https://www.ncbi.nlm.nih.gov/pubmed/12426117