Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.

In vitro work in this laboratory has identified new DNA lesions resulting from further oxidation of a common biomarker of oxidative damage, 8-oxo-7,8-dihydroguanine (OG). The major product of oxidation of OG in a nucleoside, nucleotide, or single-stranded oligodeoxynucleotide using metal ions that a...

Descripción completa

Detalles Bibliográficos
Autores principales: Burrows, Cynthia J, Muller, James G, Kornyushyna, Olga, Luo, Wenchen, Duarte, Victor, Leipold, Michael D, David, Sheila S
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241231/
https://www.ncbi.nlm.nih.gov/pubmed/12426118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241231/
https://www.ncbi.nlm.nih.gov/pubmed/12426118

Ejemplares similares