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Molecular mechanisms of in vivo metal chelation: implications for clinical treatment of metal intoxications.

Successful in vivo chelation treatment of metal intoxication requires that a significant fraction of the administered chelator in fact chelate the toxic metal. This depends on metal, chelator, and organism-related factors (e.g., ionic diameter, ring size and deformability, hardness/softness of elect...

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Detalles Bibliográficos
Autores principales: Andersen, Ole, Aaseth, Jan
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241267/
https://www.ncbi.nlm.nih.gov/pubmed/12426153