A 2-year dose-response study of lesion sequences during hepatocellular carcinogenesis in the male B6C3F(1) mouse given the drinking water chemical dichloroacetic acid.

Dichloroacetic acid (DCA) is carcinogenic to the B6C3F(1) mouse and the F344 rat. Given the carcinogenic potential of DCA in rodent liver and the known concentrations of this compound in drinking water, reliable biologically based models to reduce the uncertainty of risk assessment for human exposur...

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Detalles Bibliográficos
Autores principales: Carter, Julia H, Carter, Harry W, Deddens, James A, Hurst, Bernadette M, George, Michael H, DeAngelo, Anthony B
Formato: Texto
Lenguaje:English
Publicado: 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241306/
https://www.ncbi.nlm.nih.gov/pubmed/12515679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241306/
https://www.ncbi.nlm.nih.gov/pubmed/12515679

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