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Environmentally relevant metal and transition metal ions enhance Fc epsilon RI-mediated mast cell activation.

Upon contact with allergen, sensitized mast cells release highly active proinflammatory mediators. Allergen-mediated mast cell activation is an important mechanism in the pathogenesis of atopic asthma. Asthmatic patients are especially susceptible to air pollution. Epidemiologic studies found a posi...

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Detalles Bibliográficos
Autores principales: Walczak-Drzewiecka, Aurelia, Wyczólkowska, Janina, Dastych, Jaroslaw
Formato: Texto
Lenguaje:English
Publicado: 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241479/
https://www.ncbi.nlm.nih.gov/pubmed/12727598