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Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment.

Microarrays allow for the simultaneous measurement of changes in the levels of thousands of messenger RNAs within a single experiment. As such, the potential for the application of transcription profiling to preclinical safety assessment and mechanism-based risk assessment is profound. However, seve...

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Detalles Bibliográficos
Autores principales: Kramer, Jeffrey A, Pettit, Syril D, Amin, Rupesh P, Bertram, Timothy A, Car, Bruce, Cunningham, Michael, Curtiss, Sandra W, Davis, John W, Kind, Clive, Lawton, Michael, Naciff, Jorge M, Oreffo, Victor, Roman, Richard J, Sistare, Frank D, Stevens, James, Thompson, Karol, Vickers, Alison E, Wild, Stacey, Afshari, Cynthia A
Formato: Texto
Lenguaje:English
Publicado: 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241900/
https://www.ncbi.nlm.nih.gov/pubmed/15033596