Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours

INTRODUCTION: Phosphorylated Akt (P-Akt) is an attractive molecular target because it contributes to the development of breast cancer and confers resistance to conventional therapies. Akt also serves as a signalling intermediate for receptors such as human epidermal growth factor receptor (HER)-2, w...

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Detalles Bibliográficos
Autores principales: Kucab, Jill E, Lee, Cathy, Chen, Ching-Shih, Zhu, Jiuxiang, Gilks, C Blake, Cheang, Maggie, Huntsman, David, Yorida, Erika, Emerman, Joanne, Pollak, Michael, Dunn, Sandra E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242152/
https://www.ncbi.nlm.nih.gov/pubmed/16168126
http://dx.doi.org/10.1186/bcr1294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242152/
https://www.ncbi.nlm.nih.gov/pubmed/16168126
http://dx.doi.org/10.1186/bcr1294

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