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Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours
INTRODUCTION: Phosphorylated Akt (P-Akt) is an attractive molecular target because it contributes to the development of breast cancer and confers resistance to conventional therapies. Akt also serves as a signalling intermediate for receptors such as human epidermal growth factor receptor (HER)-2, w...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242152/ https://www.ncbi.nlm.nih.gov/pubmed/16168126 http://dx.doi.org/10.1186/bcr1294 |