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Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals

BACKGROUND: In mammals, contrary to what is usually assumed, recent evidence suggests that synonymous mutations may not be selectively neutral. This position has proven contentious, not least because of the absence of a viable mechanism. Here we test whether synonymous mutations might be under selec...

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Detalles Bibliográficos
Autores principales: Chamary, JV, Hurst, Laurence D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242210/
https://www.ncbi.nlm.nih.gov/pubmed/16168082
http://dx.doi.org/10.1186/gb-2005-6-9-r75