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Degranulating mast cells in fibrotic regions of human tumors and evidence that mast cell heparin interferes with the growth of tumor cells through a mechanism involving fibroblasts

BACKGROUND: The purpose of this study was to test the hypothesis that mast cells that are present in fibrotic regions of cancer can suppress the growth of tumor cells through an indirect mechanism involving peri-tumoral fibroblasts. METHODS: We first immunostained a wide variety of human cancers for...

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Detalles Bibliográficos
Autores principales: Samoszuk, Michael, Kanakubo, Emi, Chan, John K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242221/
https://www.ncbi.nlm.nih.gov/pubmed/16176582
http://dx.doi.org/10.1186/1471-2407-5-121