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Adaptive designs based on the truncated product method
BACKGROUND: Adaptive designs are becoming increasingly important in clinical research. One approach subdivides the study into several (two or more) stages and combines the p-values of the different stages using Fisher's combination test. METHODS: Alternatively to Fisher's test, the recentl...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242234/ https://www.ncbi.nlm.nih.gov/pubmed/16171518 http://dx.doi.org/10.1186/1471-2288-5-30 |