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Attenuated Expression of DFFB is a Hallmark of Oligodendrogliomas with 1p-Allelic Loss

Allelic loss of chromosome 1p is frequently observed in oligodendroglioma. We screened 177 oligodendroglial tumors for 1p deletions and found 6 tumors with localized 1p36 deletions. Several apoptosis regulation genes have been mapped to this region, including Tumor Protein 73 (p73), DNA Fragmentatio...

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Detalles Bibliográficos
Autores principales: McDonald, J Matthew, Dunmire, Valerie, Taylor, Ellen, Sawaya, Raymond, Bruner, Janet, Fuller, Gregory N, Aldape, Kenneth, Zhang, Wei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242250/
https://www.ncbi.nlm.nih.gov/pubmed/16156899
http://dx.doi.org/10.1186/1476-4598-4-35