Cargando…
Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer
BACKGROUND: The use of low-molecular-weight, non-peptidic molecules that disrupt the interaction between the p53 tumor suppressor and its negative regulator MDM2 has provided a promising alternative for the treatment of different types of cancer. Among these compounds, RITA (reactivation of p53 and...
| Autor principal: | |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1243243/ https://www.ncbi.nlm.nih.gov/pubmed/16174299 http://dx.doi.org/10.1186/1742-4682-2-38 |