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Evidence for a preferential targeting of 3′-UTRs by cis-encoded natural antisense transcripts

Although both the 5′- and 3′-untranslated regions (5′- and 3′-UTRs) of eukaryotic mRNAs may play a crucial role in posttranscriptional gene regulation, we observe that cis-encoded natural antisense RNAs have a striking preferential complementarity to the 3′-UTRs of their target genes in mammalian (h...

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Detalles Bibliográficos
Autores principales: Sun, Miao, Hurst, Laurence D., Carmichael, Gordon G., Chen, Jianjun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1243798/
https://www.ncbi.nlm.nih.gov/pubmed/16204454
http://dx.doi.org/10.1093/nar/gki852