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Protein Molecular Function Prediction by Bayesian Phylogenomics

We present a statistical graphical model to infer specific molecular function for unannotated protein sequences using homology. Based on phylogenomic principles, SIFTER (Statistical Inference of Function Through Evolutionary Relationships) accurately predicts molecular function for members of a prot...

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Detalles Bibliográficos
Autores principales: Engelhardt, Barbara E, Jordan, Michael I, Muratore, Kathryn E, Brenner, Steven E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1246806/
https://www.ncbi.nlm.nih.gov/pubmed/16217548
http://dx.doi.org/10.1371/journal.pcbi.0010045