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Application of Benzo(a)pyrene and Coal Tar Tumor Dose–Response Data to a Modified Benchmark Dose Method of Guideline Development

Assessment of cancer risk from exposure to polycyclic aromatic hydrocarbons (PAHs) has been traditionally conducted by applying the conservative linearized multistage (LMS) model to animal tumor data for benzo(a)pyrene (BaP), considered the most potent carcinogen in PAH mixtures. Because it has been...

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Detalles Bibliográficos
Autores principales: Fitzgerald, D. James, Robinson, Neville I., Pester, Beverly A.
Formato: Texto
Lenguaje:English
Publicado: National Institue of Environmental Health Sciences 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1247558/
https://www.ncbi.nlm.nih.gov/pubmed/15471723
http://dx.doi.org/10.1289/ehp.6427