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Increased Fidelity Reduces Poliovirus Fitness and Virulence under Selective Pressure in Mice
RNA viruses have high error rates, and the resulting quasispecies may aid survival of the virus population in the presence of selective pressure. Therefore, it has been theorized that RNA viruses require high error rates for survival, and that a virus with high fidelity would be less able to cope in...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1250929/ https://www.ncbi.nlm.nih.gov/pubmed/16220146 http://dx.doi.org/10.1371/journal.ppat.0010011 |