An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons

We have developed a highly effective method for in vivo gene silencing in the spinal cord and dorsal root ganglia (DRG) by a cationic lipid facilitated delivery of synthetic, small interfering RNA (siRNA). A siRNA to the delta opioid receptor (DOR), or a mismatch RNA, was mixed with the transfection...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Miaw-Chyi, Zhang, Dong-Qin, Ma, Shou-Wu, Huang, Yuan-Yuan, Shuster, Sam J, Porreca, Frank, Lai, Josephine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253531/
https://www.ncbi.nlm.nih.gov/pubmed/16191203
http://dx.doi.org/10.1186/1744-8069-1-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253531/
https://www.ncbi.nlm.nih.gov/pubmed/16191203
http://dx.doi.org/10.1186/1744-8069-1-29

Ejemplares similares