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An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons

We have developed a highly effective method for in vivo gene silencing in the spinal cord and dorsal root ganglia (DRG) by a cationic lipid facilitated delivery of synthetic, small interfering RNA (siRNA). A siRNA to the delta opioid receptor (DOR), or a mismatch RNA, was mixed with the transfection...

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Detalles Bibliográficos
Autores principales:	Luo, Miaw-Chyi, Zhang, Dong-Qin, Ma, Shou-Wu, Huang, Yuan-Yuan, Shuster, Sam J, Porreca, Frank, Lai, Josephine
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253531/ https://www.ncbi.nlm.nih.gov/pubmed/16191203 http://dx.doi.org/10.1186/1744-8069-1-29

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