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Use of Pharmacokinetic Modeling to Design Studies for Pathway-Specific Exposure Model Evaluation
Validating an exposure pathway model is difficult because the biomarker, which is often used to evaluate the model prediction, is an integrated measure for exposures from all the exposure routes and pathways. The purpose of this article is to demonstrate a method to use pharmacokinetic (PK) modeling...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
National Institute of Environmental Health Science
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253662/ https://www.ncbi.nlm.nih.gov/pubmed/15579416 http://dx.doi.org/10.1289/ehp.6367 |